Evaluating The Efficacy Of Morinda Citrifolia In Managing Polycystic Ovarian Syndrome And It's Impact On Bmi:A Case Study Approach

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Dr Satish Khatal , Dr.Seema Gholap , Dr. Madhavi P. Mahajan , Dr. Kirti Bhati , Dr. Sanjay A. Dhurve , Dr. Umesh Ghate

Abstract

INTRODUCTION- Polycystic ovary syndrome (PCOS) is a common female condition typified by reproductive, hyperandrogenic, and metabolic features. Polycystic ovary syndrome is a genetic condition, exacerbated by obesity. There is a close link between obesity and PCOS based on epidemiological data, and more recently corroborated through genetic studies. There are many mechanisms mediating the effects of weight-gain and obesity on the development of PCOS. The metabolic effects of insulin resistance and steroidogenic and reproductive effects of hyperinsulinemia are important mechanisms. OBJECTIVE-The objective of the study is to study of BMI in Polycystic Ovarian syndrome. MATERIALS AND METHODS-Total 117 patients were enrolled. Out of them 80 patients successfully completed the course of treatment. There were two arms of this study.one was trial arm and another was control arm. For statistical analysis, Wilcoxon Signed Rank test, Friedman test and Paired t test, Me Nemar’s test was done for different subjective and objective parameters. RESULTS There was statistically significant improvement observed in the Signs and Symptoms of, Polycystic ovarian syndrome, androgen levels, LH: FSH Ratio, Volume of the ovary and regulation of menses (p<0.05) CONCLUSION- The significantly effective in improving the signs and symptoms of Polycystic Ovary Syndrome (PCOS) in BMI. This treatment also showed positive effects on objective parameters such as the BMI.

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