Regulation of Chronic Kidney Disease By Polyherbal Syrup:“Boerhaavia diffusa L, Tribulus terrestris, & Butea mono sperma”

Abstract

Kidney is major organ for exogenous , this process occurs in the nephrons, the functional units of the kidneys. Drug induced nephrotoxicity is more common. Some of the common nephrotoxic drugs include aminoglycosides, sulphonamides, NSAIDs, anti-cancer drugs which further leads to acute kidney injury. Boerhaaviadiffusa L. This medicinal plant contains phytochemical constituents such as flavonoids, alkaloids, steroids, tri terpenoids, lipids, lignins, carbohydrates, proteins and glycoproteins. Ayurvedic literature indicates that punarnava also helps the normal kidneys functioning by illustrating its diuretic and possible nephroprotective effects against nephrotoxicity. Tribulusterrestris one of the most significant medicinal herbs that has been utilized historically for a variety of medical purposes is linn. It has diuretic properties and can help with gonorrhea and dysuria. An essential part of a human's regular physiology is the kidney,Its botanical name is Buteamonosperma. Palash flower has been traditionally used as a diuretic agent, promoting increased urine production. Diuretics can help improve kidney function by increasing the elimination of waste products and excess fluids from the body.

Method:The first step involves extracting bioactive compounds from medicinal herbs. Common extraction methods include maceration, percolation, or Soxhlet extraction using suitable solvents such as ethanol, water, or a combination of both. The extract obtained should be standardized to ensure consistent potency and efficacy.

Result: Nephroprotective effects of Boerhaavia diffusa L, tribulus terrestris, & butea mono sperma crude extract against various drug induced nephrotoxicity models and have suggested polyherbs to be an effective plant based therapeutic for amelioration of renal damage