Formulation and Evaluation of Triphala Tablets Using Direct Compression Technique

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Shivraj Vilas Mane, Ravindra Pal Singh

Abstract

Triphala is a well-known Ayurvedic formulation comprising three medicinal fruits: Emblica officinalis (amla), Terminalia bellirica (bahera), and Terminalia chebula (haritaki). Traditionally consumed in its powdered form (churna), Triphala has been used for its diverse therapeutic benefits, including antioxidant, anti-inflammatory, and digestive properties. However, the preparation and use of powdered Triphala may not be convenient for all patients, leading to the development of alternative dosage forms such as tablets. This study focuses on formulating Triphala tablets using the direct compression method, aiming to enhance patient compliance and ensure consistency in dosage. The research utilized excipients like Ludipress, Ludiflash, and Kollidon-CL to evaluate the mechanical properties of the tablets, including thickness, hardness, friability, and disintegration time. A total of twelve formulation trials were conducted to optimize the various parameters. Among these, the optimized batch demonstrated desirable physical characteristics, with a friability of 0.22%, hardness of 60.5±0.9 N, and a disintegration time of 11±0.5 minutes. These results align with pharmacopeial standards, highlighting the feasibility of using the direct compression method for the production of Triphala tablets. Overall, this study indicates that Triphala can be successfully formulated into tablets with satisfactory mechanical and disintegration properties, offering a more convenient and standardized dosage form.

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