A Review on Heterocyclic Anticancer Compounds: Recent Advances

Abstract

Heterocyclic compounds' numerous pharmacological traits and structural adaptability have made them essential in the creation of anticancer medicinal drugs. Several heterocycles with anticancer properties, including pyridine, pyrazole, and indole, are highlighted in this examine in conjunction with the structural characteristics that support their effectiveness, together with protein binding, enzyme inhibition, and DNA interaction. Important modes of action are examined, including the inhibition of DNA focused on and restore, the inhibition of protein kinase, the activation of apoptosis, and the suppression of angiogenesis and metastasis. The take a look at also looks at new tendencies inside the synthesis and design of heterocyclic anticancer pills, emphasizing inexperienced chemistry strategies, artificial pathways, and computational techniques that improve drug discovery. These trends make heterocyclic compounds a viable region for in addition study inside the development of most cancers pills in view that they provide a vast hazard for the creation of centered and efficient cancer remedies.