Comparative Study On The Role Of Punarnava Ghanavati And Modern Diuretics In Electrolyte Management In Chronic Kidney Disease (CKD)

Abstract

Chronic Kidney Disease (CKD) is a global health challenge characterised by progressive loss of renal function, often accompanied by electrolyte imbalances. Modern diuretics are the cornerstone of conventional therapy for managing fluid retention and electrolyte disturbances in CKD. However, their long-term use may lead to side effects such as hypokalemia or hyperkalemia. Punarnava Ghanavati, an Ayurvedic herbal formulation derived from Boerhavia diffusa, has emerged as a promising alternative due to its diuretic and renoprotective properties. This study compares the efficacy, safety, and mechanism of action of Punarnava Ghanavati with modern diuretics in managing electrolyte imbalances in CKD patients. The findings suggest that Punarnava Ghanavati offers a safer and more holistic approach with fewer adverse effects, thereby holding potential for integrative treatment strategies.