Assessment and Comparative Evaluation of ABO Blood Group and Oral Cancer in the Population of Madhya Pradesh

Abstract

Oral cancer is one of the leading causes of morbidity and mortality in India, particularly in regions with high tobacco consumption. The ABO blood group system has been hypothesized to influence susceptibility to various diseases, including cancers. This study evaluates the relationship between ABO blood group distribution and oral cancer in the population of Madhya Pradesh. A total of 450 participants were divided into three groups: Group A (tobacco chewers), Group B (healthy controls), and Group C (oral cancer patients). The results showed a significant association between certain ABO blood groups and oral cancer, suggesting the potential role of blood group antigens in oral cancer susceptibility.