Electrical Cardiometry Changes in Neonates with Patent Ductus Arteriosus Before and After Ventilation

Abstract

Background: Mechanical ventilation is a life-support procedure that is invasive and has a significant impact on the cardiopulmonary system. Electrical cardiometry (EC) is a method that can be used to assess hemodynamic parameters. This work aimed to evaluate the EC changes in neonates with PDA before and after ventilation.

Methods: This prospective cohort research included 25 premature infants whose gestational age was less than 37 weeks with PDA on conventional mechanical ventilation.

Results: Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), cardiac output (CO), stroke volume (SV), and systemic vascular resistance (SVV) were insignificantly different on day 1 compared to day 0. HR, CO, SV, and SVV were significantly lower on day 3 and 7 in contrast to day 0 (P<0.05). SBP, DBP, and SVR were significantly higher on day 3 and 7 when contrasted with day 0 (P<0.05). FTC was substantially lower on day 1, day 3, and 7 in comparison to day 0.

Conclusions: EC is a viable approach of determining the hemodynamic effects of negative pressure ventilation. Ventilation decreases HR, PaCO2, CO, SV, and SVV and increases SBP, DBP, pH, HCO3, and SVR.