Formulation And Evaluation Of Curcumin Based Lotion For Treating Fungal Infection

Abstract

The formulation is applied directly to the skin to treat skin conditions using a topical medication delivery method. The delivery of hydrophobic medications is a drawback of the gel formulation. Lotion, a unique medicine delivery system, can help overcome this. Lotion is a combination of two formulations: emulsion and gel. Psoriasis, acne, and fungal infections are among the skin conditions that the Lotion is used to treat. In-vitro drug release, comparative in-vitro drug release studies, SEM studies, FTIR studies, pH analysis, spredability, swelling index, drug content, globule size, and in-vitro drug release kinetics using zero order, first order, highchair model, and Korsmeyer papas model were studied and characterized for the lotion. Curcumene and the excipients used did not appear to interact chemically, according to FTIR tests. The pH of the compositions was within a range that was appropriate for skin. The swelling index and spredability were at their peak for better patient compliance.