Glycemic Index of a High Protein, High Dietary Fiber and Low carbohydrate Nutrition Formulation (NUC-RDM)

Abstract

Low Glycemic Index (GI) diets have been associated with enhancing glycemic control in type 2 diabetes patients. As a result, GI-based carbohydrate consumption is critical for both the management and prevention of type 2 diabetes. Thus, the goal of our study was to study the glycemic response of an oral nutritional supplement high in protein and dietary fiber. The Glycemic index (GI) of test food- Nuc-RDM with water was determined in 15 normal healthy participants. The test food containing 25g of available carbohydrates was given to all study participants. Furthermore, participants were tested three times with 27.5g of glucose (glucose monohydrate) drink as reference food. After consumption of reference and test foods, patients' capillary blood glucose level was measured at fasting (0 minutes), 15, 30, 45, 60, 90, and 120 minutes. Incremental area under the blood glucose curve (IAUC) over these time points was calculated. After consuming the test food, each participant's IAUC was calculated as a percentage of the mean IAUC after ingesting a standard glucose solution by the same participant. This calculation was used to determine the individual glycemic index (GI). The GI of the test food was determined by averaging these individual values. Specifically, the glycemic index of 'Nuc-RDM with water' was found to be 44±7%, classifying it as a low GI food.