Carica Papaya's Activity Related To Platelet Physiology And Thrombocytopenia

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Shilpi Arora, Vaishali Goel, Narendra Singh, Amisha Suyal, Samrah Khan, Ashish Kumar Gupta, Mamta Kumari, Ateet Srivastava

Abstract

Background: Carica Papaya, often known as Papaya, has long been used in several medical traditions for its bioactive components. Thrombocytopenia is a medical illness marked by a deficiency of platelets, resulting in the potential development of bleeding problems and various associated issues.


Objective : Papaya includes several bioactive chemicals that have been extensively researched for its possible impact on platelet function and synthesis. Papain, chymopapain, carpaine, and many flavonoids are among the noteworthy components. These chemicals have anti-inflammatory and antioxidant characteristics, and some studies propose that they could contribute to the improvement of platelet counts. Further investigation should prioritise comprehending the precise mechanisms via which these chemicals engage with the pathways implicated in platelet formation and control.


Method: To conduct a thorough evaluation of the literature, databases from Springer, Elsevier, PubMed, and Science Direct were used.


Conclusion: C Papaya has tropical leaves and potential. Papaya leaves have phytochemicals. These phytochemicals include carpaine, saponins, terpenes, alkaloids, flavonoids, and antioxidants. Vitamin- and mineral-rich Papayas are low-calorie. Fruit's healthy. Multiple scientific studies provided this data. Thrombocytopenia can result from therapy, dengue, chemotherapy, and pathologies. New and commercial C Papaya leaf doses increase platelets and prevent disintegration. No harm occurs. Carpaine, flavonoids, and antioxidants are Papaya leaf bioactives.

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