A Case Study On To Compare Efficacy Of Povidone Iodine Vs Normal Saline In Prevention Of Postpartum Endometritis And Related Febrile Morbidity In Women Going Under Elective Lscs

Abstract

Introduction: Elective Lower Segment Cesarean Section (LSCS) is a common surgical procedure worldwide, but postoperative infectious complications, particularly postpartum endometritis, remain a concern. Preoperative vaginal preparation with antiseptic agents like povidone iodine or normal saline aims to reduce these complications, yet controversy persists regarding their efficacy. This prospective cohort study compares outcomes of povidone iodine versus normal saline vaginal preparation in elective LSCS to inform evidence-based clinical practices.

Methods and Materials: A randomized controlled trial involving 123 women at Vinayaka Missions Medical College and Research Centre, Karaikal, assessed postoperative fever and postpartum endometritis. Participants underwent spinal anesthesia and catheterization before vaginal preparation with povidone iodine or normal saline. Data on demographic and clinical parameters were collected pre- and postoperatively. Statistical analysis was performed using SPSS software.

Results: The study found no significant difference in mean age, parity, or gestational age between groups. Incidence of post-CS fever was comparable between groups (3.33% vs. 6.34%, p>0.05), but wound infections were significantly lower in the povidone iodine group (3.33% vs. 14.28%, p=0.039).

Discussion: Our findings align with previous studies showing reduced postoperative infections with povidone iodine vaginal preparation. Notably, studies by Tarang Kaur et al. and Memon et al. support our results, emphasizing the efficacy of povidone iodine in reducing endometritis. The study adds to existing literature by providing evidence for optimal antiseptic practices in LSCS.