Prevalence and antibiotic susceptibility profile of Mycoplasma hominis and Ureaplasma urealyticum as well detection other vaginal pathogens in some aborted Iraqi women by using two specific Kits.

Abstract

Mycoplasma hominis and Ureaplasma urealyticum are significant opportunistic pathogens that cause complications during pregnancy. Finding out how common those pathogens were in miscarriage cases among women was the study's main goal. Detection by using rapid and direct identification kits A.F. Genital System and Urogen Well D-one, which determined other Genital Infections in abortion in a group of Iraqi women. The study was a descriptive cross-sectional study done in the period from November 2019 to December 2020. Two hundred (200) clinical specimens were collected; it was comprised only of swabs from vaginal or cervical of 176 specimens with miscarriages and 24 controls in public maternity hospitals. The positive results were 17 (9.7%) of Mycoplasma hominis in both kits. In contrast, for Ureaplasma urealyticum, positive results were 26 (14.8%) in the A.F. Genital System Kit and 27 (15.3%) in the Urogen Well D-one kit from 176 miscarriages specimens. All 24 control women revealed negative results for M. hominis and U. urealyticum in both Kits. Most of the isolates were identified as resistant to levofloxacin, Erythromycin, and Clarithromycin. At the same time, the highest sensitivity was recorded for moxifloxacin and doxycycline as on the A.F. Genital System and Urogen Well D-one Kits. In conclusion, with a 24-hour turnaround time, both kits have the potential to enable quick identification of the common organisms that lead to miscarriages in women and direct antibiotic treatment. Patients benefit greatly from this, and the need for empirical infection treatment is decreased.