Phytochemical estimation, in-vitro antioxidant and mutagenic activity of selected common agricultural weed plants

Abstract

Weed plants are good source of herbal phyto pharmaceuticals because they contained several medicinal activities such antidiabetic, anticancer, antioxidant, hepatoprotective, antipruritic, antioxidant activities. In present study the hydroalcholic extract of 8 common agricultural weed plants of Indian subcontinental eg. Fumaria indica, Celosia argentea, Chenopodium album, Corchorus olitorius, Digera muricata, Cyperus rotundus, Achyranthes aspera, and Cynodon dactylon were tested for their antioxidant and mutagenic activity. The qualitative phytochemical estimation of all plant extracts were also performed. Antioxidant activity was tested by DPPH assay and mutagenic activity and cytotoxic activity was tested by salmonella typhemurium reverse mutagen assay (AMES assay)

Quantitative phytochemical estimation of all tested weed plant showed the presence of all common secondary metabolites which are responsible for their medicinal activities. Out of all tested 8 common weed plants Cyperus rotundus showed highest in vitro antioxidant activity (IC50- 676.18 µg/ml) in DPPH assay and all selected weed plants not showed mutagenic activity on all tested doses (10, 33, 100, 333, and 1000 μg/dish) in AMES assay.