The Role Of Imprint Cytology Stains In Helicobacter Pylori Detection : A Comparative Study In a Tertiary Care Center In India

Abstract

Background: H. pylori has been related to gastrointestinal pathologies ranging from mild chronic gastritis to gastric cancers. There are numerous invasive and non-invasive techniques used to diagnose H. pylori infection. Imprint cytology simple, quick, and requires minimal additional procedures for the clinician. Smears made from biopsy samples before regular histological processing significantly reducing the waiting time for results. This rapid turnaround allows clinicians to initiate treatment during the same visit, potentially improving patient outcomes by starting therapy immediately after endoscopy. In this study, the various stains used in impression cytology for H. pylori detection were compared to RUT and traditional histopathology biopsy evaluation.