“A Comparative Clinical Study on the Effect of Mrudvikasava and Ashwagandhadyarista in Madatyaya with special reference to Alcohol Withdrawal Syndrome”

Abstract

Introduction: Alcohol Withdrawal Syndrome (AWS) is a composite and potentially life-threatening ailment that arises in individuals who have been consuming alcohol in excess and abruptly decrease or cease their alcohol intake. It comes under the heading Madatyaya in ayurveda due to same cause and general signs & symptoms. Aim and objectives: The aim of the study is to compare the clinical efficacy of Mrudvikasava and Ashwagandhadyarishta in Madatyaya W.S.R. to Alcohol Withdrawal Syndrome. Materials and Methods: After attaining endorsement of Institutional ethics committee & informed consent, 40 patients with Madatyaya were aimlessly allocated to two groups (20 in each group) for a clinical trial. In group A, Mrudvikasava was given and the drug Ashwagandhadyarishta was given in Group B for 30 days along with 15 days of follow up. Result: The clinical data shows that both the drugs presented the significant effects by reductions in CIWA-Ar Scale and Alcohol Craving Screening Questionnaire after completion of therapy. Conclusion: It can be concluded that clinically Mrudvikasava and Ashwagandhadyarishta are effective and free from any adverse outcome for the management of Madatyaya.