A Review on Potentiation of Polyherbal Formulation for the Treatment of Hyperglycemia and Inflammation

Abstract

Herbal medicine has witnessed substantial growth, underscoring its historical and modern significance in healthcare. Polyherbal formulations, blending multiple botanicals, present numerous therapeutic advantages over single-herb remedies, including synergistic effects and comprehensive efficacy against multifactorial diseases. This review explores the potential of polyherbal combinations in managing hyperglycemia and inflammation, highlighting their pharmacological interactions, advantages, and limitations. A detailed discussion on the anti-inflammatory and antidiabetic activities of various polyherbal formulations, supported by experimental evidence, is presented. Despite promising results, challenges such as formulation stability, regulatory gaps, and the need for robust clinical studies remain. By shedding light on these aspects, this review emphasizes the critical need for systematic research to optimize and validate polyherbal therapies, paving the way for their integration into evidence-based medicine.