The Regurgitation Of The Mitral Valve In Degenerative Valve Coronary Artery

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Farra Aidah Jumuddin,Sreemoy Kanti Das,Mohd Gousuddin,Afreen Banu

Abstract

Degenerative valvular alterations are the most common cause of mitral regurgitation (MR), a common valve heart condition in which blood flows retrogradely from the left ventricle towards the left atrium. The goal of this doctoral dissertation is to improve diagnostic methods, treatment paradigms, and understanding of degenerative valvular coronary artery disease by exploring the complex role of magnetic resonance imaging (MR) in this condition. The first chapter highlights the increasing clinical usefulness of magnetic resonance (MR) in the setting of degenerative valve heart disease and explains its importance. An extensive literature assessment establishes the context for the study issues and draws attention to the most pressing knowledge gaps. In order to investigate the underlying mechanisms of MR, this research takes a novel strategy that combines state-of-the-art imaging methods with genetic studies and clinical evaluations. Myocardial remodeling, hemodynamic changes, and valve degeneration all interact in intricate ways, and this study sheds new light on how MR develops. Crucial to MR evaluation is diagnostic accuracy and precision. Article offers a thorough analysis of several diagnostic methods, contrasting how well they work in real-world settings. In addition, it delves into exciting new diagnostic techniques that have the potential to transform monitoring and early detection. Article focuses on MR treatment methods for degenerative valvular heart disease. This book provides researchers and physicians with an in-depth resource for making treatment decisions by exploring medical management, surgical techniques, and new therapeutics. In Article, we discuss patient outcomes and prognostic variables, which put these treatment choices into broader perspective. In addition to expanding our knowledge of magnetic resonance (MR) in degenerative valvular heart disease, this thesis offers researchers, physicians, and legislators practical takeaways. Better patient outcomes and higher-quality care for MR patients may be possible with the integration of mechanistic insights, improved diagnostic tools, and evidence-based therapy suggestions.

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