Phytopharmacological Evaluation of Vigna mungo (L.) in experimental model of Anxiety using LPS induced anxiety model

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Mukesh Kumar Patel, Dr. Kavita R Loksh

Abstract

Vigna mungo (L.) Hepper, a lengthy, climbing plant, is utilised for the treatment of urinary reflex diseases and as a nervine tonic. Black gramme, a leguminous crop, is a nutrient-dense food abundant in vitamins, minerals, and antioxidants, bolstering immunity and promoting overall health. The investigation of phytochemical screening and the separation of bioactive chemicals from medicinal plants have attracted considerable attention in recent years, especially because of the therapeutic potential these compounds possess. The primary purpose of this work is to perform a comprehensive phytochemical investigation of Vigna mungo (L.), focusing on its secondary metabolites, including alkaloids, flavonoids, tannins, and phenolic compounds. The process entails qualitative screening via established protocols to detect the presence of these substances, succeeded by quantitative studies employing spectrophotometric techniques. Additionally, isolation protocols will be utilised to get certain bioactive constituents for comprehensive characterisation. Comprehending the phytochemical composition of these plants might elucidate their prospective health advantages and roles in traditional medicine. Prior research has demonstrated that Vigna mungo (L.) possesses anti-inflammatory, antioxidant, and antibacterial properties; yet, a comprehensive investigation of its chemical contents is still lacking. The investigation's findings indicated that all seed extracts from Vigna mungo (L.) and the accompanying phytochemical analysis produced good results, suggesting that the identified chemicals may contribute to the anti-anxiety characteristics. The evaluation of the isolated compounds' anxiolytic efficacy from the plant's methanolic extracts further substantiates this finding. The present study sought to furnish empirical validation for activities that alleviate anxiety. Further work will elucidate the precise mechanism of action of the extract and the isolated molecule responsible for its anti-anxiety efficacy, facilitating their eventual implementation as therapeutic interventions following clinical trials.

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