Correlation of CK-MB with Troponin I in Elderly Patients with Coronary Heart Disease at Baiturrahim Jambi Hospital

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Witi Karwiti, Wuni Sri Lestari, Sholeha Rezekiyah, Nasrazuhdy, Aditya Irwanda, Asrori

Abstract

Backrounds: Coronary heart disease (CHD) is a leading cause of morbidity and mortality in the elderly, characterized by a reduced blood flow to the heart muscle. Biomarkers such as CK-MB and troponin I are commonly used to assess myocardial injury and are considered important in diagnosing and monitoring CHD. This study aimed to analyze the relationship between CK-MB and troponin I levels in elderly patients with coronary heart disease (CHD) at Baiturrahim Jambi Hospital.


Methods: This study design used a cross-sectional approach with a sample of 52 CHD patients who had undergone examination of CK-MB and troponin I levels. Data analysis was performed using the Pearson correlation test to assess the relationship between variables.


Results: The mean CK-MB enzyme activity was 37.3 IU/L with a standard deviation (SD) of 11.287, while the mean troponin I level was 0.719 ng/mL with an SD of 0.590. The correlation test results showed a Pearson correlation (r) value of 0.446, indicating a moderate relationship between CK-MB enzyme activity and troponin I levels. This positive correlation indicates that an increase in CK-MB levels is followed by an increase in troponin I levels.


Conclusion: This study found a significant relationship between CK-MB and troponin I levels in elderly patients with CHD, with a positive correlation pattern.

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