The Effect of Intermittent Fasting on Glycemic Control and Insulin Resistance in Type 2 Diabetes: A Systematic Review and Meta-Analysis

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Fatima Abdalla Alshamsi, Abdulla Alsharif, Mahra Khalid Alshamsi, Haya Al-Zubaidy, Salwa Abubakr Hassan Sayih, Raniah Albairmani, Doa Jawaid Mirza, Roukaya Lamine Hamadi, Meena Alrubaye, Meera Al Shamsi, Sadaf Fatima, Nadin M-Bassam Adi

Abstract

Background: Type 2 diabetes mellitus affects the globe through its problems with blood sugar management and reduced insulin effectiveness in the body. People have trouble sticking to long-term calorie-restriction diets in traditional nutrition plans. Research shows intermittent fasting (IF) helps manage blood sugar levels and makes the body more sensitive to insulin.


Objectives: Our study analyzes how intermittent fasting affects blood sugar regulation and insulin response in people with type 2 diabetes. Our research combines existing studies to explain how IF works in T2DM treatment.


Methodology: A group of medical experts examined 25 published research reports to learn how different eating fasting techniques affect T2DM patients' body functions. Our analysis covered both randomized controlled trials and published research from clinical studies and real-world observations in respected medical journals.


Results: IF produces better blood sugar control through reduced fasting blood sugar numbers and better control over blood glucose spikes after meals. The body uses IF better to handle insulin and manage blood sugar control as well as swelling reduction. Using IF leads to weight loss while shrinking belly fat and making better blood fat profiles for a healthier metabolism. The chance of low blood sugar remains low when people use IF correctly yet each person needs special care because they react differently to fasting plans.  


Conclusion: People with Type 2 Diabetes should consider intermittent fasting as a useful eating plan to control their blood sugar and resistance to insulin. Adding intermittent fasting to standard diabetes treatments shows great promise because it brings many health advantages and helps patients follow their therapy better. Scientists should study different fasting plans to make them better while also examining if intermittent fasting keeps working safely over time.

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