It Is Reported That A Comparative – Correlation Analysis And Prognostic Criteria Of The Main Systemic Mechanisms Of Secondary Brain Damage In Combined Traumatic Brain Injury

Abstract

Today, there is a constant increase in injuries in all countries of the world. Among the causes of death and disability of the population that occurred as a result of all injuries, damage to the central nervous system comes out on top (30-40%), and in terms of its share in deaths in the most active category of the population (18-45 years old) it is ahead of cardiovascular diseases and cancer (123;129;89;112)

Due to the entire general increase in injuries, the frequency and severity of traumatic brain injuries is steadily increasing (V.V. Lebedev et al., 1981; 1995; 2001, A. Rohrret al., 1979; R.Spence et al., 1990), including up to 50-70% combined with extracranial damage (T.A. Revenko et al,1992; V.Digilio,1995). At the same time, mortality from combined traumatic brain injury (CBMT) ranges from 12% to 69% (MM). Rozhinsky et al,1976;V.V. Lebedev et al.,1992;2001, S. Bowers et al.,1990., R. Raphely ET al., 1995). According to long-term forecasts (L.B. Lichterman et al, 1979; 1997; 2001, a further increase in the incidence of neurotrauma is expected. This has led in recent decades to the inclusion in the recommendations of various congresses of traumatologists and neurosurgeons as the main task of further studying pathogenesis, developing diagnostic methods and improving the quality of treatment for patients with combined traumatic brain injury.

Research on this problem of combined trauma has been conducted in the CIS countries and abroad for no more than 15-20 years. Extensive factual material has been accumulated, and works containing valuable recommendations for the treatment of combined traumatic brain injuries have been published (G.D. Nikitin, N.K. Mityunin and E.G. Gryaznukhin, 1976; M.G. Grigoriev, N.A. Zvonkov, L.B. Lichterman and A.P. Fraerman,1977;Yu.F. Platonov, 1978; N.E. Kudryavtsev, 1980; V.V. Lebedev, V.P. Okhotsky and N.N. Kanshin, 1980; G.D. Nikitin and E.G. Gryaznukhin, 1983; V.V. Lebedev et al, 1997; 2001; A.N. Konovalov et al., 1994; 1997; 2001, R.Reding et al., 1977 Malisano LP et al. 1994), but many important aspects of the problem remain controversial and unresolved.