Antithyroid Screening of Polyherbal Formulation containing hydro-alcoholic extract of Drimiopsis kirkii Baker and Momordica charantia Linn.

Abstract

The use of medicinal plants to treat endocrine diseases is a promising and holistic approach. Herbal treatments have long been used to treat illnesses such as diabetes, thyroid dysfunction, adrenal problems, and polycystic ovarian syndrome (PCOS). Several plant-derived bioactive chemicals, including alkaloids, flavonoids, and polyphenols, have medicinal actions that promote hormonal homeostasis. However, despite their benefits, herbal medicines do have certain hazards. Potential adverse effects, contraindications, and combinations with conventional drugs underscore the significance of exercising caution and seeking professional advice. As researchers continue to investigate and evaluate the usefulness of medicinal plants, combining herbal therapies with modern medication may provide more effective and safer treatment alternatives. In the present study polyherbal formulation (tablet) was prepared from the hydro-alcoholic extract of bulb of Drimiopsis kirkii and fruits of Momordica charantia. These hyperthyroid treatments related histopathological changes of thyroid gland was dramatically inhibited by treatment of PHF-T 500 mg/kg or PTU 10mg/kg.