A Systematic Review With An Insight To Discover The Association Between Oral Lichen Planus And Thyroid Diseases
Main Article Content
Abstract
BACKGROUND
Oral Lichen Planus is an immune mediated disease which affects cutaneous tissue and oral mucosa. Thyroid disease is a common endocrine disorder which is prevalent world wide and approximately 42 million individuals in India suffer from Thyroid disorders. The objective of this systematic review is to evaluate the association between Oral Lichen Planus and Thyroid diseases.
METHODS
Articles were searched from databases such as PUBMED, Science Direct, ProQuest, Ingenta Connect and hand searched. We found 892 articles from primary databases and 2 from hand search after meeting the inclusion and exclusion criteria and six articles were assessed and included in our review, encompassing a wide geographic area.
RESULTS
Six studies were assessed with the common age group ranging between 40-70years and Oral Lichen Planus was confirmed by clinical and histopathological diagnosis. Investigations for Thyroid diseases included evaluation of T3,T4,TSH. This Systematic review found a positive correlation between OLP and Thyroid disease from the included studies.
CONCLUSION
A routine screening for Thyroid disease particularly, Hashimoto Thyroiditis is recommended upon the initial diagnosis of OLP. This procedure will facilitate early Thyroid disease diagnosis and also aid in the management of OLP.