DERMATOGLYPHIC PATTERN AMONG SOUTH INDIAN WOMEN WITH HYPOTHYROIDISM IN RELATION TO POLYCYSTIC OVARIAN SYNDROME

Abstract

Abstract Introduction

Dermatoglyphics is the study of epidermal ridge patterns (fingerprints) on the skin of the fingers, palms, toes, and soles that commence during embryological development between the sixth and seventh week of intrauterine life, and are fully formed by the 21st week. It has been used widely in fields of anthropology, genetics, and medicine and as a valuable non-invasive diagnostic tool and early assessment of risk for certain medical conditions. The presentation of PCOS in women varies from simple acne to infertility and may even be associated with disorders like Diabetes mellitus, Hypothyroidism, Dyslipidemia. This shows that the individual’s response to androgen varies i.e ethnic variation exists. They are at risk of developing Coronary artery disease, Metabolic syndrome, Type 2DM, Endometrial cancer.

Materials and Methods

A total of 300 subjects will be used for the study. Out of total number of 300 subjects, out of these 150 was normal subjects and 150 was hypothyroidism with PCOS. Female subjects of 20 to 40 years age group among south Indian population. Patients diagnosed hypothyroidism and PCOD attending the tertiary care center will be used for this study. The individuals not suffering from hypothyroidism and PCOD without any family history of hypothyroidism and PCOD will be taken as control group. Patients suffering from skin conditions which would affect the proper recording of the dermal ridges will be excluded from the study.

Results

In this study the mean age group of PCOS is 29.65 years and in control group 30.15 years. In Case Group (hypothyroidism with PCOS) mean of Right-hand Whorls patterns (2.27 with SD 1.55) was noticed and in controls was whorl patterns 2.40 with SD 1.51 was noticed. Mean Left-hand Whorls among Case was 2.20 with SD 1.56 and in control group Left-hand Whorls was 2.50 with SD 1.84. Mean Right-hand Arches among Case was 0.17 with SD 0.38 and in

control group Right-hand Arches was 0.60 with SD 0.70. Mean Left-hand Arches among Case was 0.20 with SD 0.55 and in control group Left-hand Arches was 0.50 with SD 0.85. Mean Right-hand Loops among Case was 2.57 with SD 1.48 and in control group Right-hand Loops was 2.10 with SD 1.52. Mean left-hand Loops among Case was 2.63 with SD 1.54 and in control group left-hand Loops was 2.10 with SD 1.37.

Conclusion:

Dermatoglyphics could be used as a cost effective tool for the preliminary prediction of certain medical conditions like hypothyroidism & PCOS. Early detection of the problem could eventually lead to formulate an efficient treatment plan. This would be of great help to come to some conclusion about the possibility of cause of infertility and failures of Hypothyroidism or repeated abortions. From the result of present study, it seems that now there is a time to think whether study should be made compulsory before proceeding for therapy in PCOD patients to avoid psychosocial and financial stress to the couples.