Role Of Navratri Upvasa In Modulating Oxidative Stress: An Interventional Study

Abstract

Background

Ayurveda recommends fasting as a Langhana therapy, which promotes lightness in the body. Oxidative stress occurs due to an imbalance between reactive oxygen species (ROS) and antioxidants, leading to cellular damage, chronic diseases, and aging. Studies suggest that fasting reduces oxidative stress, enhances metabolism, and extends lifespan. Religious fasting, commonly observed during seasonal transitions and is believed to detoxify and rejuvenate the body. To evaluate the impact of Navratri fasting on oxidative stress, an interventional study was conducted by assessing Superoxide Dismutase (SOD) and Malondialdehyde (MDA) levels, along with Stress Index (SI) and Protective Index (PI).

Methods

A randomized controlled trial included healthy participants divided into two groups: Navratri Upvasa and Control. Oxidative stress was evaluated using MDA levels, while antioxidant defense was measured via SOD activity. Additionally, Stress Index (SI) and Protective Index (PI) were calculated. F-tests were used to analyze pre- and post-intervention differences.

Results

The fasting group showed a significant reduction in MDA levels, indicating lower oxidative stress. SOD activity increased, reflecting enhanced antioxidant defense. Additionally, the fasting group exhibited greater reductions in SI and increases in PI compared to the control group, confirming the efficacy of Navratri fasting.

Conclusion

Navratri Upvasa effectively reduces oxidative stress and enhances antioxidant defenses, supporting its role in seasonal detoxification and overall health improvement.