Success Rates of IUI in Couples with Unexplained Infertility A cross sectional Study.

Abstract

Background: Infertility that has no known cause is found in approximately 10-20% of fertile couples globally, and routine investigations do not point to any solution. It causes stress and confusion over the decision making of the right treatment approach most of the time. IUI is the most frequently used method of the three because it is cheap, relatively painless, and moderately effective, especially for couples who have no apparent fertility problems.

Objectives: to assess success rate of IUI in cases of unexplained infertility, and possible predictors to treatment outcomes.

Study design: A cross sectional Study

Place and duration of study. Department of Obstetrics & Gynecology Gajju khan medical College Swabi from jan 2022 to dec 2023

Methods: one hundred unexplained infertility cases in five fertility clinics. Demographic details, clinical and ovarian characteristics like age and number of cycles undergoing IUI and scholars’ treatment protocols were pursued. Pregnancy rates were assessed statistically, including SD, and differences comparing the data with a p<0.05 cutoff to denote statistical significance.

Results: 100 patients the pregnancy rate was assessed to be 15% +/- 4.3% per cycle. Pregnancy rates also differed by age (p < 0.05) to be significantly higher among patients under 35. Specifically, the differences in ovarian stimulation protocols affected the outcomes directly; one protocol yielded 20% success rates while others only 10%.

Conclusions: infertility IUI has a low effectiveness its success rates depending on age and the kind of stimulation protocol used. This paper emphasizes on patient-tailored management and ongoing research in order to enhance the success rate of IUI within this group.