Intrauterine Insemination (IUI) Outcomes in Couples with Male Factor Infertility impact of Sperm Motility Count and Morphology
Main Article Content
Abstract
Background: The male factor infertility responsible for about half of all fertility issues is often treated with intrauterine insemination (IUI). Consequently, sperm concentration, motility and morphology are known to be strong predictors of IUI outcomes. Analyzing these parameters of this review may help explain how they enhance IUI success in couples with MFI.
Objectives: To evaluate the impact of sperm motility, count, and morphology on the success rate of intrauterine insemination (IUI) in couples with male factor infertility.
Study design: A Prospective study.
Place and duration of study. Department of Obstetrics & Gynecology Gajju khan medical College Swabi from 05-jan 2023 to 05-dec 2023
Methods: This Study involved data of 150 patients who had IUI for male factor infertility patients. Pre-insemination analysis of sperm samples included motility, count and morphology testing. Further analysis employing the ANOVA evaluation identified relationships and especially focusing on the differences in the pregnancy levels (p < 0.05). Standard deviations defined dispersion between parameters to determine which are correlate with better performances.
Results: From the 150 patients, the parameters with higher level of significance with IUI success included higher sperm motility (mean ± SD = 57.4 ± 10.2). Count and morphology also contributed, though to a lesser extent (mean count ± SD: 22.However, DSS/cref of PBMC was significantly lower than that of pre-SL, which averaged 5 ± 8.7 million/mL, morphology ± SD: 4.3 ± 1.2%). In the motility categories, the motility above 50 % was definitely higher in pregnancy rates and thus confirmed motility to be one of the significant predictors of IUI.
Conclusions: Sperm motility is by far the most critical determinant of IUI success, while count and morphology are also considered complementary factors. Counselling and additional therapeutic attempts directed at these sperm parameters might have the potential to increase the IUI success in male factor infertility.