Epigenetic Mechanisms in Traditional Medicine Systems: A Comprehensive Literature Review

Abstract

This literature review takes a closer look at the fascinating intersection of epigenetics and traditional medicine systems, particularly Siddha, Ayurveda, and the use of herbal remedies. It explores how bioactive compounds found in these ancient healing practices interact with epigenetic mechanisms, ultimately influencing health outcomes. We focus on three key epigenetic processes: DNA methylation, histone modifications, and microRNA regulation. These processes play crucial roles in mediating the therapeutic effects of traditional remedies. By examining the current scientific evidence, we aim to demonstrate how these age-old approaches can effectively modulate epigenetic pathways, offering potential strategies for preventing and treating a variety of diseases. This insight could lead to new and innovative medical interventions in modern healthcare. The findings of this review highlight the promise of traditional medicine systems as valuable sources of epigenetic therapies. However, we must also consider the challenges of translating these ancient practices into standardized treatments that are clinically effective. Key areas for future research include standardizing herbal preparations, enhancing the bioavailability of active compounds, and conducting rigorous clinical trials. Despite these hurdles, we believe that merging traditional medicinal knowledge with contemporary understandings of epigenetics could usher in significant advancements in personalized medicine. This integration holds the potential for more targeted, effective, and individualized treatment strategies that blend the wisdom of ancient practices with the insights of modern science.