Antibacterial and Phytochemical profiling of Pterocarpus marsupium bark extracts from Barnawapara, (C.G), India

Abstract

Pterocarpus marsupium a medicinally significant tree, traditionally used in Ayurvedic medicine and was investigated for its phytochemical composition and antibacterial activity during July,2024. The phytochemical analysis of Pterocarpus marsupiumbark extracts from three sites was likely quantifieddifferent solvents like alkaloids, flavonoids, tannins, phenols and saponins andreported percentage ranged from3.76 to 20.51%,with the methanolic and ethyl acetate extracts showing higher concentrations of these compounds.The tested substance exhibited significant inhibitory effects on the antimicrobial activity andzones of inhibition against S. aureusranged from 15.86 to 22.50 mm, E. colifrom 21.61 to 25.11 mm, St. mitisfrom 12.10 to 18 mm, P. aeruginosafrom 20.50 to 27.89 mm, E. faecalisfrom 12.20 to 20 .80 mm, M. luteusfrom 10.00 to 17.45 mm, S. typhimuriumfrom 8.67 to 20.10 mm, and B. subtilisfrom 11.00 mm to 19.80 mm respectively.The minimum inhibitory concentration (MIC) against different pathogenic bacteria ranged from 45 to 66 µg/ml.Ethyl acetate and methanol extracts were found to be more active towards the organisms tested than hexane extract.These findings demonstrate that methanolic and ethyl acetate extracts of Pterocarpus marsupium bark possess potent antibacterial activity,can be used as a potential source for developing of novel antimicrobial agents.