Green Amalgamation of Gold Nanoparticles Using Psophocarpus tetragonolobus Leaf Extract and its Bioassay

Abstract

     Due to their special physical and optical characteristics, gold nanoparticles have led to their recent rise in importance in the realm of biological applications. Other than the currently available methods, gold nanoparticles could be synthesized using Psophocarpus tetragonolobus leaf extract and examined utilizing UV-Vis and FTIR spectra, SEM and XRD. The presence of AuNPs was detected by the presence of a surface plasmon resonance band at 535 nm and peak at 601.79 cm^-1 respectively from UV-Vis and FTIR spectra. Using SEM, the morphology of amalgamated AuNPs was found spherical in shape. XRD helped to state the crystalline nature of AuNPs. Further, AuNPs demonstrated significant anti-inflammatory activity.  In addition to being tested for their antifungal properties against Candida albicans and Aspergillus niger, amalgamated AuNPs have also been tested against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Bacillus subtilis for their antibacterial activity. Overall, the findings of this study shed light on strategies for designing nano drugs which makes it a potential candidate for therapeutic applications.