Synthesis And Characterisation Of Srtio3/Fe2o3/Zno Nanocomposites And Its Antibacterial Activity Against Dental Pathogens

Abstract

Introduction Nanoparticles are spherical particles composed of natural or artificial polymers, having size of 10 and 500 nm. These particles have a wide range of potential applications and NPs in particular have demonstrated broad-spectrum antibacterial properties against both Gram-positive and Gram-negative bacteria. Metal nanoparticles containing metals such as strontium, titanium, iron and zinc have been increasingly used for their antibacterial properties in recent times.

Materials and methods ZnO was prepared by using zinc chloride and sodium bicarbonate, SrTiO3 was obtained from strontium nitrate and titanium tetrachloride in the aqueous solution of NH3  and Fe2O3  was made by dissolving 10g of FeSO4.7H2O

in 100 ml of double distilled water, to which 2 to 3 drops of concentrated sulfuric acid were added. The ternary nanocomposite was prepared by taking 0.98 g of prepared SrTiO3/ZnO which was dispersed in 40 mL of ethanol. 0.02 g Fe2O3 powder is added into the above solution and again stirred upto 12 hours. A  rosy white powder  is obtained after volatilization of the ethanol and drying at 80 °C in the air. , which is the nanocomposite.

Results The XRD pattern displayed several sharp peaks indicating that the material is polycrystalline, the functional groups present in the nanocomposite was studied using FTIR where ZnO showed a peak at 1134 cm−1, Fe2O3 at 3796 cm−1 and SrTiO3 at 580 cm−1. SEM images showed SrTiO3 in the form of cubic crystals, spherical/granular particles that are characteristic of ZnO. EDX spectrum results showed the presence of 27.7% zinc and 34.4% oxygen. Culture plates show significant clear zones of inhibition , confirming broad-spectrum antibacterial effect, with values of 22–25 mm.

Conclusion The synthesis and characterization of SrTiO3/Fe2O3/ZnO nanocomposites was successful and was proved using data from XRD, SEM and FTIR. Its antibacterial activity against S.mutans and E.faecalis was also studied and at higher concentration, its zone of inhibition was similar to the control