Modern Aspects Of Clinical And Laboratory Diagnostics Of Streptococcal Tonsillitis

Abstract

Annotation: Purpose of the study - Examine the clinical and diagnostic features of the to S.pyogenes.  Materials and methods. A prospective study of 223 patients with older than 7 years with a diagnosis of acute tonsillitis hospitalized in 2018-2019 to the angin branch Clinical and laboratory data of patients were analyzed. The bacteriological study of the nasopharyal mucus, as well as the immunophromatographic method of the express test ("StreptotestR" France), was carried out with a tonsillite, as well as the immunochromatographic method for determining the β-hemolytic streptococcus group A. Results: From 223 S.pyogenes nasopharyal mucus samples identified in 79 patients, from them bacteriological method S.pyogenes allocated from 53 (23,7%) patients, from Staphylococcus aureus 42 (18,8%) of patients, Staphylococcus Aureus + Candida spp at 27 (12,2%) patients, Staphylococcus spp - in 15 (6,7%), Staphylococcus Epidermidis - 12 (5,4%) patients, in 74 (33,2%) of patients received a negative result. The results of the express test during comparative analysis with the results of bacteriological studies have shown that out of 53 patients with S.pyogenes etiology of from the bacteriological examination, streptotest was positive in 47 cases, and in 26 patients the result of streptotest was positive in the absence of S.pyogenes According to the results of bacteriological research.

Conclusion: The widespread use of rapid diagnostic methods, such as express tests, will allow at an early stage to determine the streptococcal etiology of tonsillites and carry out reliable accounting of streptococcal angins. Given the development of various complications after the transfer of Streptococcal Angiin, it is important to study the dissemination issues, the epidemiological characteristics of the pathogen, clinical aspects that will allow to develop effective prevention measures in a timely manner.