Insilico Evaluation Of Phytoconstitents From Mangifera Indica By Using Protein In Breast Cancer

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Shilpa Savata Kolhe, J. B. Veeramalini, K. Chandrasekhar, V Santhoshi Pravallika, Bhagyashree Mishra, C. Aarthi Priya, Snehal T Hase, N D Nizamuddin

Abstract

In India, cancer ranks as the second most deadly disease. India is home to a wide variety of cancers, including lung, pancreatic, breast, and prostate cancers. In India, breast cancer is the most prevalent type of cancer across all age categories. There are three common forms of breast cancer, with triple-negative breast cancer having the greatest death rate. Lasers, chemotherapy, and replacement are treatment options for breast cancer. Although all of these therapy approaches are successful in curing this illness, they are too costly and have numerous adverse effects. Indians have practiced Ayurveda for centuries. Ayurvedic practitioners use many ayurvedic plants to cure a variety of illnesses, including cancer, diabetes, and inflammation. Ayurveda utilizes Mangifera indica as one such plant. veda. The flowering plant Mangifera indica is a member of the Anacardiaceae family. People use it to treat conditions such as stomach and skin issues, among others. Here, we used molecular docking and bioinformatic methods to investigate the various components of Mangifera indica's anti-cancer properties. Therefore, using a variety of bioinformatic approaches, we have investigated the potential of all the phytochemicals in mango plants to prevent breast cancer. The best phytochemical breast cancer candidate is mugiferin.

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