A Review On Antiviral Drugs On Floating Drug Delivery System

Abstract

Floating drug delivery systems (FDDS) have emerged as an innovative approach for enhancing the pharmacokinetics and bioavailability of drugs. Floating drug-delivery system (FDDS) is a gastro retentive pharmaceutical preparation that could delay the gastric residence time to obtain adequate bioavailability of a drug. The system is floating in the gastric fluid for a low substance density than the aqueous medium. Antiviral drugs, which play a crucial role in the management of viral infections, can benefit from the use of floating drug delivery systems, as they often exhibit poor solubility, limited bioavailability, and susceptibility to degradation in the gastrointestinal tract. This review focuses on the application of FDDS in the delivery of antiviral drugs, highlighting their advantages, formulation strategies, types of floating systems, and challenges associated with their development and implementation.