Association between Ocular Perfusion Pressure, Pressure to Cornea Index and Open-Angle Glaucoma – A Case-Control Study
Main Article Content
Abstract
INTRODUCTION
Glaucoma is a progressive eye condition with numerous risk factors, including advanced age, elevated intraocular pressure (IOP), familial predisposition, elevated systolic and low diastolic blood pressure, and decreased central corneal thickness. The study aimed to examine the mean ocular perfusion pressure and pressure cornea index in newly diagnosed glaucoma patients and compare these parameters with those of healthy individuals without glaucoma.
MATERIALS AND METHODS
The study investigated the association between IOP and factors in patients with primary open angle glaucoma (POAG) compared to control subjects. It involved 52 participants, divided into two groups: 26 recently diagnosed POAG and 26 healthy subjects without glaucoma. The study was approved by the Institutional Ethics Committee and included informed consent and clinical examinations. The age range of the participants was between 41 and 70 years, and both sexes were represented in the study.
RESULTS
The study found that POAG subjects had significantly higher mean values of mean ocular perfusion pressure (MOPP) compared to control subjects. The older age group was found to be more prone to developing glaucoma. The mean values of PCI in POAG subjects were also significantly higher than those in control subjects.
CONCLUSION
Integrating systemic blood pressure management can optimize ocular perfusion and slow disease progression. Furthermore, incorporating pressure cornea index into glaucoma diagnostic algorithms may assist in predicting disease progression and guiding treatment decisions.