Urine Microalbumin And Hba1c As Early Markers Of Chronic Kidney Disease In Type 2 Diabetes Mellitus

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Margono, Furaida Khasanah, Fitria Endah Janitra, Tri Prabowo, Woro Umi Ratih, Budi Setiawan

Abstract

The correlation between urine microalbumin and HbA1c levels is a significant early indicator of chronic kidney disease (CKD) in individuals with type 2 diabetes mellitus (T2DM). Microalbuminuria, characterised by an increased urine albumin-to-creatinine ratio, frequently serves as the initial indicator of diabetic nephropathy, which may advance to end-stage renal disease if not identified promptly. This study aims to ascertain the correlation between urine microalbumin and creatinine levels and HbA1c in individuals diagnosed with type 2 diabetes. This research was an analytical observational study employing a cross-sectional strategy. This study involved 40 individuals with type 2 diabetes who received routine check-ups at Sultan Agung Hospital in Semarang. Jaundice, lipemic and hemolyzed serum samples will not be used for HbA1c testing. The study results indicated no correlation between HbA1c and microalbumin or creatinine levels in patients with type 2 diabetes. The duration of diabetes mellitus patients was quite short, averaging 5.73 years of illness.

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