Antioxidant potential of Trichosanthes dioica Roxb. Extract

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Mudit Kumar, Pushpendra Kumar, Mona Piplani

Abstract

 Trichosanthes dioica Roxb.  have been used since ancient times in the traditional medicinal systems like, Ayurveda, Siddha, Chinese and many other system of medicines in the treatment of various ailments. The fruits have been used topically in various conditions like, sprains, swellings, wounds and bruises. In present work Phytochemical and pharmacological evaluation of various extract of Trichosanthes Dioica Roxb.  leaves was performed to proves as Anti-oxidant agent. In India, abundant precious plants are used in ayurveda as well as traditionally for the treatment of inflammation. The discovery of inflammatory inhibitors from natural origin will present an opportunity for a medicinal chemist to design novel, structurally diverse selective inflammatory inhibitors. The present study was undertaken based on the ethno medical background of the plants such as Trichosanthes Dioica Roxb.  leaves part of these plants were selected for anti oxidant activity. Methanol extract of Trichosanthes Dioica Roxb.  leaves extract at 400 µg/ml concentrations displayed 55.1±0.33, maximum activity compared to other all extracts. Methanol extract of Trichosanthes Dioica Roxb.  leaves (TDL) was evaluated for

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